Last update: 2021 / 07 / 13
Hui Vivian Chiu
Google Scholar | ORCID | @HchiuT
hchiu at caltech.edu
EDUCATIONS
2021 PhD | California Institute of Technology (Caltech) | Dr. David Anderson
2014 Visiting Student | HHMI Janelia Research Campus | Dr. Barry Dickson
2011 MS | National Taiwan University (NTU) | Dr. Yi-Chun Wu
WORK EXPERIENCE
2011 - 2013 Research assistant | Cincinnati Children's Hospital | Dr. Chieh Chang
AWARDS & FELLOWSHIPS
2021 Milton and Francis Clauser Doctoral Prize | Caltech
- Awarded to the best 2 PhD theses across all academic divisions
2021 Lawrence L. and Audrey W. Ferguson Prize | Caltech
- Awarded to the best 2 Biology PhD theses
2008 Research Creativity Award | Ministry of Science and Technology (MOST), Taiwan
- Nationwide top 5% undergraduate research performance
2008 Distinguished Undergraduate Thesis Award | NTU
2008 College Student Research Training Fellowship | MOST
PUBLICATIONS
Research Articles
Chiu, H.*, Hoopfer, E.D., Coughlan, M.L., Pavlou, H.J., Goodwin, S.F., and Anderson, D.J.* (2021). A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila. Cell 184, 507-520.e16.
*Co-corresponding authors
-Featured in Nature Reviews Neuroscience, "Fly Fighters"
-Co-conceptualized the project, performed the experiments, analyzed the data, and co-wrote the manuscript
Jung, Y., Kennedy, A., Chiu, H., Mohammad, F., Claridge-Chang, A., and Anderson, D.J. (2020). Neurons that function within an integrator to promote a persistent behavioral state in Drosophila. Neuron 105, 322-333.e5.
-Cloned the nls-GCaMP, the enhancers, and generated the transgenic flies
Chiu, H., Zou, Y., Suzuki, N., Hsieh, Y.-W., Chuang, C.-F., Wu, Y.-C., and Chang, C. (2018). Engulfing cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1. Nature Communication 9, 4842.
-Co-conceptualized the project, performed the experiments, analyzed the data, co-wrote the manuscript
Yu, J.-Y., Kim, J., Holland, D.B., Mou, Y., Chiu, H., Blake, G.A., Lee, W., Guo, G.-L. (2018). Multiphoton structured thin-plane imaging with a single optical path. Optical letters 43, 5271-5274.
-Provided the biological samples
Watanabe, K., Chiu, H., Pfeiffer, B.D., Wong, A.M., Hoopfer, E.D., Rubin, G.M., and Anderson, D.J. (2017). A circuit node that integrates convergent input from neuromodulatory and social behavior-promoting neurons to control aggression in Drosophila. Neuron 95, 1112-1128.e7.
-Performed the in vivo calcium imaging experiment and analyzed the data
Dong, X., Chiu, H., Park, Y.J., Zou, W., Zou, Y., Özkan, E., Chang, C., and Shen, K. (2016). Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions. ELife 5, e11008.
-Contributed unpublished reagents and data
Flytzanis, N.C., Bedbrook, C.N., Chiu, H., Engqvist, M.K., Xiao, C., Chan, K.Y., Sternberg, P.W., Arnold, F.H., and Gradinaru, V. (2014). Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons. Nature Communications 5, 4894.
-Generated the transgenic C. elegance reagents and performed the in vivo imaging experiment
Davenport, A.M., Collins, L.N., Chiu, H., Minor, P.J., Sternberg, P.W., and Hoelz, A. (2014). Structural and functional characterization of the alpha-tubulin acetyltransferase MEC-17. Journal of Molecular Biology 426, 2605-2616.
-Generated the transgenic worms and performed behavioral analysis
Chiu, H.*, Schwartz, H.T.*, Antoshechkin, I., and Sternberg, P.W. (2013). Transgene-free genome editing in Caenorhabditis elegans using CRISPR-Cas. Genetics 195, 1167-1171.
* Equal contribution
-Co-conceptualized the project, performed the experiments, analyzed the data, and co-wrote the manuscript
Zou, Y.*, Chiu, H.*, Zinovyeva, A., Ambros, V., Chuang, C.F., and Chang, C. (2013). Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers. Science 340, 372-376.
* Equal contribution
-Co-conceptualized the project, performed the experiments, and analyzed the data
Zou, Y., Chiu, H., Domenger, D., Chuang, C.F., and Chang, C. (2012). The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction. Science Signaling 5, ra43.
-Performed the experiments and analyzed the data
Reviews
Chiu, H., and Chang, C. (2013). Rejuvenating nerve cells in adults. Aging 5, 485-486.
Chiu, H., Alqadah, A., Chuang, C.F., and Chang, C. (2011). C. elegans as a genetic model to identify novel cellular and molecular mechanisms underlying nervous system regeneration. Cell Adhesion & Migration 5, 387-394.
PRESENTATIONS
Talks
2020 Neurolunch | Caltech
2018 Cold Spring Harbor Laboratory (CSHL) Meeting: Neuronal Circuits
2017 Biolunch | Caltech
2015 Biolunch | Caltech
2013 19th International C. elegans Meeting | Genome Editing Workshop
Posters
2018 HHMI Science Meeting
2018 CSHL Brains & Behavior: Order & Disorder in the Nervous System
2013 19th International C. elegans Meeting
Guest Lecture
2017 Physics of Measurement | Caltech
Introduced Drosophila neuroscience research to physics students
Outreach
2021 Eliot Arts Academy Science Night | "Sex, Fear, and Anger: Understand Your Brain and Emotions"
Explained neuroscience research to middle school students
2021 Virtual Active Science Engagement | "Be you, and better"
Shared my academic pathfinding journey with undergraduates worldwide
SERVICES
2020 Judge | Doris S Perpall Summer Undergraduate Research Fellowships (SURF) Speaking Competition | Caltech
2015 - 2017 Organizer | BBE Graduate Student Seminar Series | Caltech
2015 Judge | SURF Symposium | Caltech
2014 Session Chair | SURF Symposium | Caltech
MENTORING EXPERIENCE
2021 mentored i-STEM Scholar | high school students from first-generation and low-income background
2019 mentored Caltech WAVE Fellow | underrepresented or educationally disadvantaged students
-The student was awarded the "Genentech Fellow" title for her research performance
2016 - 2020 mentored several rotation students
SKILLS
Language MATLAB
Python
R
Software Illustrator
Photoshop
Arduino
SolidWorks
Laboratory Two-photon calcium imaging
Genetic-based experiments
Molecular cloning
Animal behavior analysis
Microdissection
CRISPR-Cas