Last update: 2021 / 07 / 13

Hui Vivian Chiu
Google Scholar | ORCID | @HchiuT
hchiu at caltech.edu

EDUCATIONS

2021 PhD | California Institute of Technology (Caltech) | Dr. David Anderson

2014 Visiting Student | HHMI Janelia Research Campus | Dr. Barry Dickson

2011 MS | National Taiwan University (NTU) | Dr. Yi-Chun Wu

WORK EXPERIENCE

2011 - 2013 Research assistant | Cincinnati Children's Hospital | Dr. Chieh Chang

AWARDS & FELLOWSHIPS

2021 Milton and Francis Clauser Doctoral Prize | Caltech

- Awarded to the best 2 PhD theses across all academic divisions


2021 Lawrence L. and Audrey W. Ferguson Prize | Caltech

- Awarded to the best 2 Biology PhD theses

2008 Research Creativity Award | Ministry of Science and Technology (MOST), Taiwan

- Nationwide top 5% undergraduate research performance

2008 Distinguished Undergraduate Thesis Award | NTU


2008 College Student Research Training Fellowship | MOST

PUBLICATIONS

Research Articles


Chiu, H.*, Hoopfer, E.D., Coughlan, M.L., Pavlou, H.J., Goodwin, S.F., and Anderson, D.J.* (2021). A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila. Cell 184, 507-520.e16.

*Co-corresponding authors

-Featured in Nature Reviews Neuroscience, "Fly Fighters"

-Co-conceptualized the project, performed the experiments, analyzed the data, and co-wrote the manuscript


Jung, Y., Kennedy, A., Chiu, H., Mohammad, F., Claridge-Chang, A., and Anderson, D.J. (2020). Neurons that function within an integrator to promote a persistent behavioral state in Drosophila. Neuron 105, 322-333.e5.

-Cloned the nls-GCaMP, the enhancers, and generated the transgenic flies


Chiu, H., Zou, Y., Suzuki, N., Hsieh, Y.-W., Chuang, C.-F., Wu, Y.-C., and Chang, C. (2018). Engulfing cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1. Nature Communication 9, 4842.

-Co-conceptualized the project, performed the experiments, analyzed the data, co-wrote the manuscript


Yu, J.-Y., Kim, J., Holland, D.B., Mou, Y., Chiu, H., Blake, G.A., Lee, W., Guo, G.-L. (2018). Multiphoton structured thin-plane imaging with a single optical path. Optical letters 43, 5271-5274.

-Provided the biological samples


Watanabe, K., Chiu, H., Pfeiffer, B.D., Wong, A.M., Hoopfer, E.D., Rubin, G.M., and Anderson, D.J. (2017). A circuit node that integrates convergent input from neuromodulatory and social behavior-promoting neurons to control aggression in Drosophila. Neuron 95, 1112-1128.e7.

-Performed the in vivo calcium imaging experiment and analyzed the data


Dong, X., Chiu, H., Park, Y.J., Zou, W., Zou, Y., Özkan, E., Chang, C., and Shen, K. (2016). Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions. ELife 5, e11008.

-Contributed unpublished reagents and data


Flytzanis, N.C., Bedbrook, C.N., Chiu, H., Engqvist, M.K., Xiao, C., Chan, K.Y., Sternberg, P.W., Arnold, F.H., and Gradinaru, V. (2014). Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons. Nature Communications 5, 4894.

-Generated the transgenic C. elegance reagents and performed the in vivo imaging experiment


Davenport, A.M., Collins, L.N., Chiu, H., Minor, P.J., Sternberg, P.W., and Hoelz, A. (2014). Structural and functional characterization of the alpha-tubulin acetyltransferase MEC-17. Journal of Molecular Biology 426, 2605-2616.

-Generated the transgenic worms and performed behavioral analysis


Chiu, H.*, Schwartz, H.T.*, Antoshechkin, I., and Sternberg, P.W. (2013). Transgene-free genome editing in Caenorhabditis elegans using CRISPR-Cas. Genetics 195, 1167-1171.

* Equal contribution

-Co-conceptualized the project, performed the experiments, analyzed the data, and co-wrote the manuscript


Zou, Y.*, Chiu, H.*, Zinovyeva, A., Ambros, V., Chuang, C.F., and Chang, C. (2013). Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers. Science 340, 372-376.

* Equal contribution

-Co-conceptualized the project, performed the experiments, and analyzed the data


Zou, Y., Chiu, H., Domenger, D., Chuang, C.F., and Chang, C. (2012). The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction. Science Signaling 5, ra43.

-Performed the experiments and analyzed the data


Reviews


Chiu, H., and Chang, C. (2013). Rejuvenating nerve cells in adults. Aging 5, 485-486.


Chiu, H., Alqadah, A., Chuang, C.F., and Chang, C. (2011). C. elegans as a genetic model to identify novel cellular and molecular mechanisms underlying nervous system regeneration. Cell Adhesion & Migration 5, 387-394.

PRESENTATIONS

Talks


2020 Neurolunch | Caltech


2018 Cold Spring Harbor Laboratory (CSHL) Meeting: Neuronal Circuits


2017 Biolunch | Caltech


2015 Biolunch | Caltech


2013 19th International C. elegans Meeting | Genome Editing Workshop

Posters


2018 HHMI Science Meeting


2018 CSHL Brains & Behavior: Order & Disorder in the Nervous System


2013 19th International C. elegans Meeting


Guest Lecture


2017 Physics of Measurement | Caltech

Introduced Drosophila neuroscience research to physics students


Outreach


2021 Eliot Arts Academy Science Night | "Sex, Fear, and Anger: Understand Your Brain and Emotions"

Explained neuroscience research to middle school students

2021 Virtual Active Science Engagement | "Be you, and better"

Shared my academic pathfinding journey with undergraduates worldwide

SERVICES

2020 Judge | Doris S Perpall Summer Undergraduate Research Fellowships (SURF) Speaking Competition | Caltech

2015 - 2017 Organizer | BBE Graduate Student Seminar Series | Caltech

2015 Judge | SURF Symposium | Caltech

2014 Session Chair | SURF Symposium | Caltech

MENTORING EXPERIENCE

2021 mentored i-STEM Scholar | high school students from first-generation and low-income background


2019 mentored Caltech WAVE Fellow | underrepresented or educationally disadvantaged students

-The student was awarded the "Genentech Fellow" title for her research performance

2016 - 2020 mentored several rotation students

SKILLS


Language MATLAB

Python

R


Software Illustrator

Photoshop

Arduino

SolidWorks


Laboratory Two-photon calcium imaging

Genetic-based experiments

Molecular cloning

Animal behavior analysis

Microdissection

CRISPR-Cas